Welcome to the gene-environment, gene-gene interaction home page. Quanto, a program to calculate sample size, is available through this website.
Version 1.2.0 - Added the 2 degree of freedom test for the gene and interaction term together.
Version 1.2.1 - Fixed a bug in saving when the interaction term varied. Displays routines were updated.
Version 1.2.2 - Fixed a bug in the wizard for the inheritance mode. Fixed a display issue with varying parameters for continuous traits.
Version 1.2.3 - Fixed a bug in dialog for selecting the 2 degree of freedom test. It could not be selected using the wizards.
Version 1.2.4 - Improved function for calculating power for 2 degree of freedom test. This also fixed a bug that caused the program to exit to Windows. The installation program was updated to include support for Windows Vista.
This program computes sample size or power for association studies of genes, gene-environment interaction, or gene-gene interaction. Available study designs include the matched case-control, case-sibling, case-parent, and case-only designs. Quanto is a 32-bit Windows application requiring Windows 95, 98, NT, 2000, ME, XP, 2003, or Vista to run. The graphical user interface allows the user to easily change the model and view the results without having to edit an input file and rerun the program for every model. The results of a session are stored to a log file. This log can be printed or saved to a file for reviewing at a later date. An option is included to create a text file of the log that can be imported into other documents.
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