The Analytical Facility Core is directed by Dr. William Hinds and co-directed by Dr. Antonio Miguel. Dr. Hinds is a Professor of Environmental Health Sciences in the School of Public Health at UCLA. He is director of the Industrial Hygiene Program, a member of the Particle Center, and Co-PI on the EPA Supersite grant. He is an expert on the properties and measurement of aerosols. Dr. Miguel is an analytical chemist with many years of experience in environmental analytical chemistry. The specialized supporting laboratories are linked to the Analytical Facility Core through the primary analytical laboratory (PMCAL) and Dr. Miguel. The Directors of the supporting laboratories are Drs. Kym Faull, Shane Que Hee, and Ed Ruth.

Co-Directors Drs. Hinds and Miguel are responsible for planning and coordination of all Analytical Facility Core functions. This includes priority setting, defining long-term equipment needs, ensuring appropriate quality control/quality assurance practices, periodic meetings with research cores, establishing priorities between the NIEHS Center and the Particle Center, addressing occupational safety and health practices, providing oversight for all equipment maintenance, developing chain of custody methodology for sample transfer, establishing training programs for technical staff, assuring the adequacy of support facilities, and establishing procedures for meeting institutional requirements.

The PMCAL is located in the UCLA School of Public Health, where other components of the Exposure Assessment Research and Analytical Facility Cores are also located. The three supporting analytical laboratories are located on the UCLA campus in the Departments of Civil and Environmental Engineering, Environmental Health Sciences, and Chemistry & Biochemistry. The exposure assessment service laboratories and the aerosol science laboratories are located in the School of Public Health adjacent to the primary analytical laboratory.