The Molecular Biology and Sample Processing Facility Core (MBSPFC) provides a single Core service to assist researchers to develop sample handling protocols, receive newly collected samples, monitor incoming sample quality, process samples, distribute/ship samples to laboratories, store excess samples for future use, and maintain a system for tracking samples and retrieving selected sample data. The biological samples handled may include blood, tissue, urine, other body fluids, smears, and scrapings (e.g., buccal cells), etc. The majority of the specimens are received for the purpose of performing specific molecular biological tests within the Core. A significant proportion is received for initial processing (for example obtaining buffy coats from blood samples) and temporary storage until the specimens are shipped to collaborators. The samples are then logged in with a unique identifying number.

The Core personnel work with researchers in developing sample processing protocols. They also help with the selection, ordering, and budgeting of supplies and equipment needed for sample collection or processing. The personnel may answer questions about shipping requirements or practical considerations. For example, researchers may be alerted to conditions affecting certain tests. The order in which multiple tubes of blood are drawn affects platelet counts. Exposure to light reduces concentrations of plasma carotenoids. Prolonged contact with the original stopper on a blood collection tube may interfere with measurement of organochlorine compounds and some minerals.