11/22/2009
 
Research Cores
 
Respiratory Effects
Cancer
Study Design
and Statistical Methodology
Exposure Assessment
Study Investigators:
Craig Jones
Rob McConnell
Co-Investigators:
Kiros Berhane
Jean Richardson
Study
Co-ordinator:

Judith Cahero
 
Respiratory Effects Research Core
Community Intervention Project on Asthma
Description:
The major goal of this study is to determine whether a comprehensive environmental health education program, enhanced by least toxic integrated pest management for cockroach control, will result in reduction in concentrations of antigens in household dust and/or improvement in clinical status among these children. The study population will consist of 200 children with chronic persistent asthma randomly selected from the 3,000 asthmatics identified by the school-based Breathmobile program. Children will be randomized into two groups: (1) 100 children will continue to receive usual care from the Breathmobile; (2) 100 children will receive usual care plus a standardized antigen reduction strategy (STARS), a community based, family oriented environmental health training program. Exposure to environmental asthma triggers in the home will be assessed by measuring concentrations of dust mite antigen, and cockroach antigen, in house dust. Outcomes of interest include change in knowledge, change in concentrations of antigen in house dust, school absence, clinical assessment of asthma severity, and medication use. Covariates to be considered include exposure to environmental tobacco smoke, indoor and outdoor air pollutants, housing characteristics (such as molds, mildew, air conditioning) and demographics (such as family size, gender, ethnicity).