11/22/2009
 
Research Cores
 
Respiratory Effects
Cancer
Study Design
and Statistical Methodology
Exposure Assessment
Study Investigator:
John Peters
Co-Investigators:
Ed Avol
Kiros Berhane
Jim Gauderman
Frank Gilliland
Henry Gong
William Linn
Rob McConnell
Duncan Thomas
 
 
Respiratory Effects Research Core
Children's Health Study
 
The Chronic Health Effects of Ambient Air Pollutants
This ten-year longitudinal study aims to answer three questions: Do children living in high air pollution areas suffer deleterious chronic respiratory effects? Do children living in high pollution areas suffer greater rates of acute respiratory illness, more severe respiratory illness and/or exacerbation of underlying disease (e.g., more asthma episodes in asthmatics)? Are there sub-populations of children more susceptible to the effects of air pollution than their peers? These questions are being addressed by studying 6,000 school children in 12 communities with varying air pollution levels and patterns in Southern California through pulmonary function testing, absence monitoring and questionnaire approaches. Health endpoints are being compared to extensive measurements of air pollution including ozone, NO2, PM10 and acid vapors both at the ambient (community) level and at the individual level, over time (see Exposure Assessment Research Core). Other factors that contribute to respiratory disease are also being considered both for their direct effects and also to control confounding.
The CHS is supported primarily by the California Air Resources Board (CARB), with additional support from the NIEHS Center, and from the EPA.