Transdisciplinary research is being performed to assess cultural and migratory factors affecting tobacco use and its prevention among youth in multi-cultural settings. The research goal is to improve understanding of the separate and interactive roles of culture, cultural transitions, genetics, and individual behavior relative to smoking and ETS exposure. To accomplish this, researchers will carry out longitudinal trials to assess promising approaches to tobacco use and tobacco exposure prevention across a range of pluralistic and monolithic cultural settings. This will involve research to clarify California and Pacific Rim population characteristics and trends essential to TTURC's aims of culture-specific population trials, and studies and population needs research for facilitating public policy. The research team will develop comprehensive, valid and reliable measures of factors related to culture/acculturation, individual characteristics, and tobacco use and related behaviors. Investigators will utilize the TTURC's program of research to inform tobacco use and tobacco exposure programs and policies, and will work to assure the highest quality program of training and career development in transdisciplinary tobacco use research is achieved. The research team will provide outreach to the California and Pacific Rim communities in conjunction with our Center's COEP, to assure that community needs are acknowledged and addressed in the center's programs of research and training, and facilitate access of TTURC researchers to community settings and resources.