11/22/2009
 
Research Cores
 
Respiratory Effects
Cancer
Study Design
and Statistical Methodology
Exposure Assessment
Core Director:
Duncan Thomas
 
Core Members
Publication List
Statistical Research Grants
Goals & Objectives
Future Research Initiatives
 
 
Study Design and Statistical Methodology Research Core
Publication List
On the use of spatial survival models to examine the association between long-term exposure to ambient air pollution and mortality in the American Cancer Society Cohort. Air & Waste Management Assoc Crit Rev Proc. Burnett, R. T., M. Jerrett, R. Ma, C. A. Pope, III, D. Hughes and D. Krewski (2006).
Children's exposure to nitrogen dioxide in Sweden : investigating environmental injustice in an egalitarian country. J Epidemiol Community Health 60(3): 234-41. Chaix, B., S. Gustafsson, M. Jerrett, H. Kristersson, T. Lithman, A. Boalt and J. Merlo (2006).
Physiologically-based pharmacokinetic modeling platform for genetic and exposure effects in metabolic pathways. Genetic Epidemiology 29: 234. Du, L., D. V. Conti and D. C. Thomas (2006).
Air pollution and children--an unhealthy mix. N Engl J Med 355(1): 78-9. Gauderman, W. J. (2006).
Ethnic and racial differences in the smoking-related risk of lung cancer. N Engl J Med 354: 333-42. Haiman, C. A., D. O. Stram, L. R. Wilkens, M. C. Pike, L. N. Kolonel, B. E. Henderson and L. Le Marchand (2006).
Particulate air pollution and mortality in the magalopolis. Air & Waste Management Assoc Crit Rev Proc. Jerrett, M., R. T. Burnett, K. Ito, G. Thurston, Z. Ross, E. Hughes, C. A. Pope, III, R. Ma, E. E. Calle, M. J. Thun and D. Krewski (2006).
Exploring uncertainties in the health benefits from air quality improvements. Stochast Environ Res & Risk Assessment. Jerrett, M., K. B. Newbold, R. T. Burnett, G. Thurston, R. Lall, C. A. Pope, III, R. Ma, P. DeLuca, M. J. Thun, E. E. Calle and D. Krewski (in press).
Air pollution and asthma incidence in children. Proc Amer Thoracic Soc 3: A23. Jerrett, M., K. Shankardass, J. Gauderman, K. Berhane, N. Kunzli, F. Lurmann, E. Avol, J. Peters, F. Gilliland, J. Molitor and R. McConnell (2006).
Li, D. and D. V. Conti (2006). BCCC method: a powerful and robust test for GxE interaction. Genet Epidemiol: NEED PAGES.
Maclachlan, J. C., M. Jerrett, T. Abernathy, M. Sears and M. J. Bunch (2007). Mapping health on the Internet: A new tool for environmental justice and public health research. Health Place 13(1): 72-86.
Marjoram, P., J. Chang, P. W. Laird and K. D. Siegmund (2006). Cluster analysis for DNA methylation profiles having a detection threshold. BMC Bioinformatics 7: 361.
Millstein, J., D. V. Conti, F. D. Gilliland and W. J. Gauderman (2006). A testing framework for identifying susceptibility genes in the presence of epistasis. Am J Hum Genet 78(1): 15-27.
Ross, Z., P. B. English, R. Scalf, R. Gunier, S. Smorodinsky, S. Wall and M. Jerrett (2006). Nitrogen dioxide prediction in Southern California using land use regression modeling: potential for environmental health analyses. J Expo Sci Environ Epidemiol 16(2): 106-14.
Sahsuvaroglu, T., A. Arain, P. Kanaroglou, N. Finkelstein, B. Newbold, M. Jerrett, B. Beckerman, J. Brook, M. Finkelstein and N. L. Gilbert (2006). A land use regression model for predicting ambient concentrations of nitrogen dioxide in Hamilton , Ontario , Canada . J Air Waste Manag Assoc 56(8): 1059-69.
Schlesinger, R. B., N. Kunzli , G. M. Hidy, T. Gotschi and M. Jerrett (2006). The health relevance of ambient particulate matter characteristics: coherence of toxicological and epidemiological inferences. Inhal Toxicol 18(2): 95-125.

Indoor time-microenvironment-activity patterns in seven regions of Europe . J Expo Sci Environ Epidemiol. Schweizer, C., R. D. Edwards, L. Bayer-Oglesby, W. J. Gauderman, V. Ilacqua, M. Juhani Jantunen, H. K. Lai, M. Nieuwenhuijsen and N. Kunzli (2006).

The association between community socioeconomic factors and prevalent asthma in southern California school children. Proc Amer Thoracic Soc 3: A153. Shankardass, K., R. McConnell, Z. Tatalovich, J. P. Wilson and M. Jerrett (2006).
Modeling exposures for DNA methylation profiles. Cancer Epidemiol Biomarkers Prev 15(3): 567-72. Siegmund, K. D., A. J. Levine, J. Chang and P. W. Laird (2006).
Competing definitions of contextual environments. Int J Health Geogr 5: 55. Tatalovich, Z., J. P. Wilson, J. E. Milam, M. L. Jerrett and R. McConnell (2006).
Are we ready for genome-wide association studies? Cancer Epidemiol Biomarkers Prev 15(4): 595-8. Thomas, D. C. (2006).
Two stage genetic association studies. Encycolpedia of Clinical Trials. R. C. Elston. New York , Wiley: in press. Thomas, D. C. and D. V. Conti (2006).
Caveats on Bayesian model averaging in time series studies of air pollution and mortality. J Toxicol Environ Health A: in press. Thomas, D. C., M. Jerrett, N. Kuenzli, T. Louis, F. Dominici, S. Zeger, J. Schwartz, R. Burnett and D. Bates (2006).
Thomas, D. C., J. S. Witte and S. Greenland (2007). Dissecting effects of complex mixtures: who's afraid of informative priors? Epidemiology 18(3): in press.
Wang, H. and D. O. Stram (2006). Optimal two-stage genome-wide association designs based on False Discovery Rate. Computat Statist Data Anal 5: 457-65.
Wang, H., D. C. Thomas, I. Pe'er and D. O. Stram (2006). Optimal two-stage genotyping designs for genome-wide association scans. Genet Epidemiol 30: 356-368.
Re: "Have sperm densities declined? A reanalysis of global trend data" (Letter). Environ Health Perspect 1998; 106:A420.
Becker S, Berhane K.
Automatic smoothing parameter selection in non-parametric models for longitudinal data. J Appl Stochastic Models and Data Analysis 1998; 13:289-296.
Berhane K, Rao JS.
Generalized additive models for longitudinal data. Can J Stat 1998; 26:517-535.
Berhane K, Tibshirani RJ.
Estimation of excess absolute risk from case-control data using Aalen's linear regression model. Biometrics 1997; 53: 690-697.
Borgan O, Langholz B.
Risk set sampling designs for proportional hazards models. In Statistical analysis of medical data: New developments. Everitt BS, Dunn G (eds). London; Arnold, 1998, pp. 75-100.
Borgan O, Langholz B.
Exposure stratified case-cohort studies. Lifetime Data Analysis 2000; in press.
Borgan O, Langholz B, Samuelsen SO, Pogoda J, Goldstein L.
Residential magnetic fields predicted from wiring configurations: I. Exposure model. Bioelectromagnetics 1999: 20: 399-413.
Bowman J, Thomas DC, Jiang F, Peters J.
A Bayesian approach to measurement error in dose response analysis: application to the atomic bomb survivors cohort. In Uncertainties in radiation dosimetry and their impact on dose-response analyses. Ron E, Hoffman FO (eds). NCI Monograph 1999; 99-4541: 100-109.
Deltour I, Richardson S, Thomas D.
Simultaneously modeling censored survival data and repeatedly measured covariates. Statistics in Medicine 1996: 15:1663-1685.
Faucett C, Thomas D.
A Gibbs sampling approach for handling missing data in pedigree studies. Computing Science and Statistics 1997a; 29:250-258.
Gauderman WJ, Faucett CL.
Detection of gene-environment interactions in joint segregation and linkage analysis. Am J Hum Genet 1997b; 61:1189-1199.
Gauderman WJ, Faucett CL.
Joint segregation and linkage analysis of quantitative traits compared to separate analyses. Genetic Epidemiol 1997c; 14:993-998.
Gauderman WJ, Faucett CL, Morrison JL, Carpenter CL.
Association between air pollution and pulmonary function growth in Southern-California school-aged children. Am J Respir Care Med 2000; in press.
Gauderman WJ, McConnell R, Gilliland F, London S, Thomas D, Avol E, Berhane K, Rappaport E, Lurmann F, Margolis H, Peters J.
Analysis of gene-smoking interaction in lung cancer. Genet Epidemiol 1997d; 14:199-214.
Gauderman WJ, Morrison JL, Carpenter CL, Thomas DC.
A joint test of linkage and GxE interaction using affected sib-pairs. Genet Epidemiol 1999a; 17 (Suppl 1):S563-S568.
Gauderman WJ, Morrison JL, Siegmund K, Thomas DC.
Evidence for age-specific genetic relative risks in lung cancer. Am J Epidemiol 2000; 151: 41-50.
Gauderman WJ, Morrison JL.
Family-based association studies. Monogr Natl Cancer Inst 1999b: 26: 31-37.
Gauderman WJ, Witte JS, Thomas DC.
The role of interacting determinants in the localization of genes. In: Genetic Dissection of Complex Traits: Challenges for the Next Millenium; Rao DC (ed). Advances in Genetics, Academic Press: 2000; in press.
Gauderman WJ, Thomas DC.
Maternal smoking during pregnancy, environmental tobacco smoke exposure and childhood lung function. Thorax 2000: in press.
Gilliland FD, Berhane K, McConnell R, Gauderman WJ, Rappaport E, Vora H, Avol E, Peters J.
Selected study design issues addressed in the development of the USC consortium's colorectal cancer family registry. Monogr Natl Cancer Inst 1999: 26: 89-93.
Haile R, Siegmund KD, Gauderman WJ, Thomas DC.
Re: "Combined analysis of matched and unmatched case-control studies: Comparison of risk estimates from different studies" (Letter). Am J Epidemiol 1999a; 150:219-220.
Huberman M, Langholz B.
Application of the missing-indicator method in matched case-control studies with incomplete data. Am J Epidemiol 1999b; 150: 1340-1345.
Huberman M, Langholz B.
Latency and cancer risk. In: Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides: Veterans and Agent Orange: Update 1996, chapter 8. Institute of Medicine, National Academy Press, Washington, D.C.
Langholz B.
Case-cohort study. In Encyclopedia of Statistics, Armitage P, Colton T (eds). Chichester: Wiley, 1998a, pp. 497-503.
Langholz B.
Case-control study, nested. In Encyclopedia of Statistics, Armitage P, Colton T (eds). Chichester: Wiley, 1998b, pp. 514-519.
Langholz B.
Estimation of absolute risk from nested case-control data. Biometrics 1997; 53: 767-774.
Langholz B, Borgan O.
Fitting logistic models using conditional logistic likelihood when there are large strata. Computing Science and Statistics 1997; 29: 551-555.
Langholz B, Goldstein L.
Risk set sampling in epidemiologic cohort studies. Stat Science 1996; 11:35-53.
Langholz B, Goldstein L.
Risk of disease in Vietnam veterans. In Committee to Review the Health Effects in Vietnam Veterans of Exposure to Herbicides: Veterans and Agent Orange: Update 1996, Appendix B. Institute of Medicine, National Academy Press, Washington, D.C.
Langholz B, Pike MC.
Cohort studies for characterizing measured genes. Monogr Natl Cancer Inst 1999a: 26: 39-42.
Langholz B, Rothman N, Wacholder S, Thomas DC.
Latency analysis in epidemiologic studies of occupational exposures: application to the Colorado plateau uranium miners cohort. Am J Ind Med 1999b; 35:246-256.
Langholz B, Thomas D, Xiang A, Stram DO.
Ascertainment correction in rate ratio estimation from case-sibling control studies of variable age-at-onset diseases. Biometrics 1999c; 55:1129-1136.
Langholz B, Ziogas A, Thomas DC, Faucett C, Huberman M, Goldstein L.
Segregation analysis of continuous phenotypes using higher sample moments. Am J Hum Genet 1996; 58:213-224.
Lee H, Stram D.
Air pollution and daily hospital admissions in metropolitan Los Angeles. Environ Health Perspectives 2000: in press.
Linn WS, Szlachcic Y, Gong H, Kinney PL, Berhane K.
Lung cancer risk in relation to the CYP2E1 RsaI genetic polymorphism among African-Americans and Caucasians in Los Angeles county. Pharmacogenetics 1996; 6:151-158.
London S, Daly A, Cooper J, Carpenter C, Ding L, Navidi W, Idle, J.
Air pollution and bronchitic symptoms in Southern California children with asthma. EnvironHealth Perspect 1999; 107:757-760.
McConnell R, Berhane K, Gilliland F, London SJ, Vora H, Avol E, Gauderman WJ, Margolis, HG, Lurman F, Thomas DC, Peters JM.
Bidirectional case-crossover designs for exposures with time trends. Biometrics 1998; 54:596-605.
Navidi W.
A study of twelve southern California communities with differing levels and types of air pollution. II. Effects on pulmonary function. Am J Respir Crit Care Med 1999a; 159:768-775.
Peters JM, Avol E, Gauderman WJ, Linn WE, Navidi W, London SJ, Margolis H, Rappaport E, Vora H, Gong H, Thomas DC.
A study of twelve southern California communities with differing levels and types of air pollution. I. Prevalence of respiratory morbidity. Am J Respir Crit Care Med 1999b; 159:760-767.
Peters JM, Avol E, Navidi W, London SJ, Gauderman WJ, Lurman F, Linn WE, Margolis H, Rappaport E, Gong H, Thomas DC.
Missense mutations in disease genes: A Bayesian approach to evaluate causality. Am J Hum Genet 1998; 62:1516-1524.
Petersen G, Giovanni P, Thomas D.
Innovative Study Designs for the Genetic Epidemiology of Cancer. Nat Cancer Inst Monograph, 1999; vol 26.
Schaid D, Thomas DC, Whittemore AS (eds.).
Modeling hazard functions in families. Genet Epidemiol 1998a; 15:147-171.
Siegmund KD, McKnight B.
Association test using unaffected sibling versus pseudo-sibling controls. Genet Epidemiol 1999a; 17 (suppl 1):S731-S736.
Siegmund KD, Gauderman WJ, Thomas DC.
Modeling disease incidence rates in families. Epidemiology, 1998b; 9:557-562.
Siegmund KD, Province MA, Higgins M, Williams R, Keller J, Todorov AA.
A frailty approach for modeling diseases with variable age of onset in families: the NHLBI Family Heart Study. Statistics in Medicine 1999c; 18:1517-1528.
Siegmund KD, Todorov AA, Province MA.
Multi-stage sampling for disease family registries. Monogr Natl Cancer Inst 1999d: 26: 43-48.
Siegmund KD, Whittemore AS, Thomas DC.
A strategic view of randomized trial design in low-incidence paediatric cancer. Statistics in Medicine 18:1183-97, 1999.
Sposto R, Stram DO.
Meta-analysis of published data using a linear mixed-effects model. Biometrics 1996; 52:536-544.
Stram DO.
Measurement error correction for the analysis of lung cancer mortality in the Colorado Plateau uranium miner cohort. In Uncertainties in radiation dosimetry and their impact on dose-response analyses, Ron E, Hoffman FO (eds). NCI Monograph 1999a; 99-4541:192-195.
Stram DO, Langholz B, Huberman M, Thomas D.
Correcting for exposure measurement error in a reanalysis of lung cancer mortality for the Colorado plateau uranium miners cohort. Health Physics 1999b; 77:265-275.
Stram DO, Langholz B, Huberman M, Thomas DC.
Re: "Associations of race/ethnicity, education, and dietary intervention with the validity and reliability of a food frequency questionnaire" (Letter). Am J Epidemiol 1998; 148:819-20.
Stram DO, Pike MC.
Analysis of time to death after transplantation when transplants are only given to patients in remission. Biometrics 1996:1079-1086.
Stram DO, Sather H, Wang L.
Relative risk modeling. In Encyclopedia of Biostatistics, Armitage P, Colton T (eds). Chichester: Wiley, 1998a, pp. 3763-3771.
Thomas DC.
New techniques for the analysis of cohort studies. Epidemiologic Reviews 1998b; 14:122-134.
Thomas DC.
Design of gene characterization studies: an overview. Monogr Natl Cancer Inst 1999a: 26: 17-23.
Thomas DC.
Re: "Case-parents design for gene-environment interaction" by Schaid (Letter). Genet Epidemiol 1999b; in press.
Thomas DC.
The Utah fallout study: How uncertainty has affected estimates of dose-response. In Uncertainties in radiation dosimetry and their impact on dose-response analyses, Ron E, Hoffman FO (eds). NCI Monograph 1999c: 99-4541:217-224.
Thomas DC.
Genetic epidemiology with a capital "E." Genet Epidemiol 2000: 18: in press. (Abstract published at 17: 228.)
Thomas DC.
Residential magnetic fields predicted from wiring configurations: II. Relationships to childhood leukemia. Bioelectromagnetics 1999a:414-420.
Thomas DC, Jiang F, Bowman J, Peters J.
A GEE approach to modeling disease concordance within sibships in relation to multiple markers and exposure factors. Genet Epidemiol 1999b; 17(suppl 1):S737-S742.
Thomas DC, Qian D, Gauderman WJ, Siegmund K, Morrison JL.
A Bayesian approach to multipoint mapping in nuclear families. Genet Epidemiol 1997; 14:903-908.
Thomas DC, Richardson S, Gauderman J, Pitkaniemi J.
Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: Basic family designs. Am J Epidemiol 1999; 149:693-705.
Witte J, Gauderman WJ, Thomas DC.
Comparison of case-control to full cohort analyses under model misspecification. Biometrika 1999; 86:221-226.
Xiang A, Langholz B.
Exposure measurement error in time-series studies of air pollution. Environ Health Perspect 2000 (in press).
Zeger SL, Dominici F, Samet JM, Thomas DC, Schwartz J, Dockery DW, Cohen AJ.